Liverpool were drawn against Sparta Prague in the last 16 of the Europa League, while Brighton face another tough test in their first season in Europe with a draw against Roma.
West Ham will again face their group opponents Freiburg, while Rangers will face Benfica.
All four British teams have the advantage of playing their second matches at home, thanks to being top of their group.
They travel to play their first legs on March 7, while the second legs will be played a week later on March 14.
Freiburg vs West Ham
After facing each other in the group stages, West Ham will be confident of reaching the quarter-finals after home and away wins before Christmas. Nayef Aguerd headed in the winner at the Europa-Park Stadium in October before they finished 2-0 at the London Stadium thanks to goals from Mohammed Kudus and Edson Alvarez. The difference, however, was that David Moyes’ side were in good form in the first half of the season, but are currently in a run of eight games without a win. The Germans’ attack will be led by experienced Italian international Vincenzo Grifo, 30, who is their top scorer in all competitions this season.
Winners: West Ham
Roma vs Brighton
The Italians sacked Jose Mourinho last month, reflecting their season. But they are finalists from last season and have a pedigree in the league. They also have a team with Romelu Lukaku, Paulo Dybala and Lorenzo Pellegrini, who are match winners against every opponent. The appointment of Daniele De Rossi has led to a run of wins to help them go into the match in good form, while Brighton have run hot and cold of late under Roberto De Zerbi. They scored fourteen goals in recent wins against Sheffield United (twice) and Crystal Palace, but also lost 4-0 to Luton.
Winners: Rome
Sparta Prague vs Liverpool
The Czech champions started the season in the Champions League but were eliminated in the play-off stages, although they were not defeated outright and went out on away goals to Copenhagen, who went on to beat Manchester United. In their Europa League group they finished second to Real Betis and behind Rangers, with whom they drew at home and lost away. However, Liverpool will not fear any team in their current form and their only problem is juggling fixtures and getting players fit again. They have managed to avoid the tougher encounters in the last sixteen stage and it will be a disappointment if they do not progress further.
Winners: Liverpool
Europa League last 16 draw: as it happened…
11:33 GMT
The complete draw of the last sixteen of the Europa League
Sparta Prague vs Liverpool
Marseille vs Villarreal
Roma vs Brighton
Benfica vs Rangers
Freiburg vs West Ham
Sporting Lisbon vs Atalanta
AC Milan vs Slavia Prague
Qarabag vs Bayer Leverkusen
11:30 GMT
What will the teams think?
Liverpool and West Ham will be happy to have avoided the more dangerous-looking sides, but Brighton have once again been given a very difficult task after going through a group that included Marseille, Ajax and AEK Athens.
Roma are one of the sides with the richest pedigrees left in the tournament, and some parts of their traveling support will worry Sussex Police.
Rangers face a big test against a legendary club in Benfica, but the Glasgow side are looking to rise to the occasion.
Everyone will be relieved to have avoided in-form Leverkusen and the long journey to Qarabag (Azerbaijan).
11:26 GMT
When are the matches?
As a reminder, all British teams, as they were group winners, will be away for the first leg on Thursday 7 March and at home for the second leg on 14 March.
11:22 GMT
Last three tapes
The last three drawn matches were:
Sporting Lisbon vs Atalanta
AC Milan vs Slavia Prague
Qarabag vs Bayer Leverkusen
11:19 GMT
Hammers to face Freiburg again
Freiburg vs West Ham, a repeat of the group stage
11:17 GMT
Rangers take on Benfica
Benfica vs Rangers
11:16 GMT
Tough draw for Brighton!
Roma vs Brighton
11:14 GMT
Marseille vs Villarreal
Marseille vs Villarreal is the next away match
11:13 GMT
Liverpool gets Sparta Prague
Sparta Prague vs Liverpool is the first equal match
11:11 am GMT
The technical details
A UEFA official named Tobias explains that group winners will be drawn against a play-off winner from another country, with the play-off winners drawn first.
11:07 GMT
Dublin is calling
Qarabag gets some credit for being the first Azebaijan team to reach the knockouts and then they roll out the red carpet for former Man Utd and Republic of Ireland defender John O’Shea – because the final is in Dublin
11:06 GMT
Suits at home
UEFA Deputy Secretary General Giorgio Marchetti has taken to the stage to announce the upcoming draw…
11:04 GMT
Who is in the pots?
The eight Europa League group stage winners have been seeded and will face the winners of the knockout round and play-offs.
Seeded teams
Atalanta (ITA)
Brighton (ENG)
Leverkusen (DE)
Liverpool (ENG)
Rangers (SCO)
Slavia Prague (CZE)
Villarreal (ESP)
West Ham (NL)
Unseeded teams
AC Milan (ITA)
Benfica (POR)
Freiburg (DE)
Marseille (FRA)
Qarabag (AZE)
Roma (ITA)
Sparta Prague (CZE)
Sporting CP (POR)
11:03 GMT
We are on our way…
The broadcast is on its way from Nyon and they’ve quickly cut to a montage of the teams battling for glory in Europe’s second division with inappropriately dramatic music…
11:02 GMT
Who peeked through?
The play-off stage, which involved teams dropped out of the Champions League, concluded last night.
Here are the results:
Bodo Glimt 1-2 Ajax (Agg 3-4)
Dinamo Zagreb 1-1 Real Betis (2-1 on aggregate)
Ludogorets Razgrad 0-1 Napkin (Agg 0-1)
Eintracht Frankfurt 1-2 Union Sint-Gillis (Agg 3-4)
Ferencvaros 0-1 Olympiakos (Agg 0-2)
Legia Warsaw 0-3 Molde (Agg 2-6)
Slovan Bratislava 0-1 Sturm Graz (Agg. 1-5)
10:56 GMT
Pots and balls ready to go…
10:55 GMT
Group stage summary
A quick summary of the group stage…
Liverpool topped Group E despite losing two games, the 3-2 defeat at Toulouse and a 2-1 final round defeat at Union SG.
West Ham, last year’s Europa Conference League winners, won Group A ahead of Freiburg thanks to five wins and just one defeat.
Brighton recovered from a home defeat to AEK Athens with four wins and a draw in top Group B, ahead of Marseille and Ajax.
Rangers won Group C by one point against Sparta Prague, despite two draws and one loss.
10:47 GMT
Four British teams qualified
Four British teams will learn their opponents for the last 16 of the Europa League today when the draw takes place in Nyon, Switzerland.
Liverpool, Brighton, West Ham and Rangers all qualified after topping their groups.
This means that they will be away for the first leg on Thursday, March 7, and will be home for the second leg on March 14.
The draw starts at 11am UK time, although we can no doubt expect quite a bit of preamble before the balls are picked.
Aston Villa, meanwhile, will take part in the Europa Conference League draw, which will take place later, from the afternoon.